Progress Report

Progress Report

Progress Report Vol 11 A Periodic Newsletter for Our Loyal Contributors A Message from the President D R I V FALL 2009 MS Society Announces Ne...

2MB Sizes 0 Downloads 2 Views

Progress Report Vol 11

A Periodic Newsletter for Our Loyal Contributors

A Message from the President

D

R

I

V

FALL 2009

MS Society Announces New endMS Regional Research and Training Centres

E

Going Strong

The Multiple Sclerosis Society of Canada believes that collaboration is the quickest way to end MS! Yves Savoie

The MS Society of Canada’s Family & Friends Drive is in its 6th year! We’re so pleased with the success of this critical program, and grateful for every one of our volunteer participants. Just last year, the Family & Friends Drive went online, making it even easier to contact people you know who might be interested in supporting the MS Society. If you haven’t been called to participate, sign up online at www.mssociety.ca/en/give/family&friends.htm

A few tips for the upcoming Drive: • W  hen you’re asking your friends to support the MS Society, don’t forget that you might have some interested friends next door! Ask your neighbours to participate. • I f you belong to a book group or church group, let the other members know you’re raising money for MS. Every new supporter helps! • Look out for your volunteer kit in the mail.

A Monthly Donor on Giving to the MS Society Through our pre-authorized giving program, donors pledge their support on a monthly basis. It’s easy and convenient! As a monthly donor to the MS Society, you’ll ensure that we have a steady flow of funds for research. You’ll also receive a copy of our Annual Review, a complimentary pen set, invitations to participate in our teleconferences on MS research and bi-annual newsletter updates keeping you informed about the ongoing fight against MS. We spoke with Peter L. about why he chooses to make a monthly gift to the MS Society.

“I had actually forgotten that I was a monthly donor, since it’s so easy to just give and not think about it. It’s so much simpler than sending a cheque every few months. I don’t mind helping out; it is nice to be able to see some progress against a disease that is so much of a mystery.” Please help us make a cure for multiple sclerosis a reality with your pre-authorized gift – see the attached reply form, or visit us online at http://www.mssociety. ca/en/give/monthly-giving.htm

175 Bloor Street East, Suite 700 Toronto, Ontario M4W 3R8 Toll Free: (800) 361-2985

t hd Thompson

Habib

Denison

Job Title: MSC 0909 Progress Report Paper/Stock: 60# OFFSET Specs: 11 x 17” Newsletter (outside) Special Instructions: FOLDS IN HALF TO 8.5” x 11” AND AGAIN IN THIRDS Colors: Black & PMS 032

At the MS Society of Canada, we understand times are difficult for many Canadians. The global recession has taken a toll on all of us in some way. For our organization, the economy has had a direct impact on our ability to raise funds, threatening the research we fund and the services we provide. But multiple sclerosis does not relent in tough times, and neither will we. The MS Society remains committed to ending this disease! And we’re grateful and humbled that you are still with us. We know that what we are asking you to do now is more difficult than it was last year. Your support is more important than ever to the estimated 55,000-75,000 Canadians with MS. I hope you enjoy reading about our plans to keep fighting MS in this issue: from the studies we’ve helped fund, to the new network of endMS Regional Research and Training Centres we established earlier this year. And I also hope you will be touched by the personal stories from our scholarship recipients, whose lives your generosity has helped change. Thank you again for your support. It means so much.

Yves Savoie President and Chief Executive Officer Multiple Sclerosis Society of Canada MSC-NL4-F09

Canada is home to some of the best MS researchers in the world, spread across our vast country from Newfoundland to British Columbia. With the establishment of the endMS Research and Training Network and its five endMS Regional Research and Training Centres, our top researchers are now able to increase their collaboration and provide new education and training opportunities for research trainees. The five endMS RRTCs include over 100 affiliated researchers and 250 trainees. Researchers and trainees affiliated with each centre will collaborate, exchange information and increase their knowledge and skill in MS research through such activities as conferences, workshops, and inter-lab exchanges. Each centre comprises multiple academic institutions and teaching hospitals within a geographic region:

• Western-Pacific, covering British Columbia and Saskatchewan • Atlantic, covering the four Atlantic provinces • Manitoba-Ontario, excluding Ottawa • Quebec-Ottawa • Alberta

And for the next three years, each centre will receive $100,000 per year to fund research and training activities – funded entirely by the MS Society of Canada. The MS Society’s goal for the endMS Network is to accelerate discovery in the field of MS in Canada by increasing the capacity to conduct MS-focused research.

Meet More of our Scholarship Recipients

Promising Results from Clinical Trials of Two New Oral Therapies The positive results of two oral therapies were presented for the first time at the annual meeting of the American Academy of Neurology earlier this year. The two experimental oral therapies, cladribine and fingolimod, are each in Phase III clinical trials. Cladribine is a chemotherapy that depletes some of the immune cells thought to be involved in MS attacks. Results from a study of oral cladribine in 1,326 people with relapsing-remitting MS showed that after nearly two years, the relapse rate in those on cladribine was reduced compared to those on the placebo. About 80% of those on cladribine were relapse-free over the two years, versus about 60% of those on the placebo. In the fingolimod study, 1,292 people with relapsing-remitting MS who had experienced one or more relapses over the previous year were split into three groups: one group taking Avonex (an approved and frequently prescribed drug for MS); another taking a low dose of fingolimod; and a third group taking a higher dose of fingolimod. Eighty to 83% of those on either dose of fingolimod remained relapse-free over the year, compared to 69% of those on Avonex. Several longer phase III clinical trials are currently underway, including one involving people with primary progressive MS. And company press releases for both therapies suggested that they plan to apply for marketing approval at the end of 2009, to make the drugs available to the general public.

t hd Thompson

Habib

Denison

Job Title: MSC 0909 Progress Report Specs: 11 x 17” Newsletter (inside) Colors: Black & PMS 032

SUPPORTED BY BILLY TALENT & FRIENDS

Prenatal Exposure to Vitamin D May Lessen MS Risk Research funded in part by the MS Society of Canada has found evidence of a relationship between vitamin D and a common genetic variant which may alter the risk of developing multiple sclerosis. The research suggests that vitamin D deficiency during gestation and early childhood may increase the risk of a child developing the disease. University of Oxford researchers have shown that there is a direct relationship between DRB1*1501, a genetic variant associated with MS, and vitamin D. “This research represents an important development in our understanding of the cause of MS,” says Dr. Paul O’Connor, national scientific and medical advisor for the MS Society of Canada. “The evidence implicating vitamin D deficiency as a key factor in MS continues to mount,” says Dr. O’Connor. “Vitamin D insufficiency is emerging as a key factor of MS in children, and in adults. This finding links important work in two streams of research, namely genetics and epidemiology, and illustrates the important role the MS Society plays in solving what is a very complex disease.” Dr. O’Connor cautions that the study does not provide guidelines on vitamin D dosage and that any decisions on treatment or supplementation should be made in consultation with a trained physician.

Paper/Stock: 60# OFFSET Special Instructions: FOLDS IN HALF TO 8.5” x 11” AND AGAIN IN THIRDS

The MS Society of Canada Scholarship Program, supported by Billy Talent and Friends, is a post-secondary scholarship program for teens and young adults in Canada who have MS or who have a parent with MS. Last year, 80 young men and women received scholarships from the program. Below are excerpts from their own inspiring words on how MS has affected them.

Jessica Moskaluke, Saskatchewan Brandon University – Criminal Justice

Taylor McDonald, Ontario Durham College – Sports Administration

“When I was four years old, my father was diagnosed with MS. Eventually he became a paraplegic, and lost his ability to talk, feed himself, or even see… …When times get rough, I think of him and say, ‘Would he want me to feel sorry for myself?’ He never complained about his illness and he would want me to keep living my life the best I knew how.” When Jessica was 16 years old, she organized a rock concert and snowboard competition at the Asessippi Ski Lodge, with all proceeds going to the MS Society of Canada in memory of her father, Tim Moskaluke. “We raised about five thousand dollars, all of which went to the MS Society. I couldn’t have been happier, and although my dad wasn’t there with me, I know he guided me every step of the way.”

“Having your life affected by MS made me realize that it is the joy and love you bring to others that is the ultimate reward. My aunt has had MS since she was fifteen years old; my mom was diagnosed two years later at age nineteen… If you ever happen to meet me you will notice that I wear the red Hope – MS wristband in a reminder to be strong like my mother and aunt, to never give up and persevere through even the toughest of challenges.”

Kaitlin Curtiss, Ontario Brock University – Biology/Psychology “During my time with the doctors at the Hospital for Sick Children, I developed a keen interest in the field of pediatric neurology and a resolve to impact children’s lives as my doctors had impacted mine. While multiple sclerosis has had a profound effect on my physical state, it is not what defines me. I have still been able to live my life and will continue to do so regardless of the effects of MS.”

Tasli Shaw, British Columbia University of British Columbia – Psychology “The story of multiple sclerosis in my life lies within my mother, who has been under the grip of this chronic illness for nearly three decades… It is like having a troublesome relative over twenty-four hours a day, and try as we may, this is one relative that will not leave without a fight. MS has made my mother an immensely strong willed person, full of courage and determination. And despite the ongoing struggle my mother faces, through all the hardship day-to-day life throws at her, the single most outstanding gift she has given me is rock steady positivity. In scary and mysterious times, through the painful and traumatic events which come along with MS, my mother can smile.”

If you are interested in making a gift to the scholarship program, please contact: Nicole Mellin, Assistant Vice-President, National Client Services Research & Programs Phone: 1-866-922-6065, ext. 3004, [email protected]

Meet More of our Scholarship Recipients

Promising Results from Clinical Trials of Two New Oral Therapies The positive results of two oral therapies were presented for the first time at the annual meeting of the American Academy of Neurology earlier this year. The two experimental oral therapies, cladribine and fingolimod, are each in Phase III clinical trials. Cladribine is a chemotherapy that depletes some of the immune cells thought to be involved in MS attacks. Results from a study of oral cladribine in 1,326 people with relapsing-remitting MS showed that after nearly two years, the relapse rate in those on cladribine was reduced compared to those on the placebo. About 80% of those on cladribine were relapse-free over the two years, versus about 60% of those on the placebo. In the fingolimod study, 1,292 people with relapsing-remitting MS who had experienced one or more relapses over the previous year were split into three groups: one group taking Avonex (an approved and frequently prescribed drug for MS); another taking a low dose of fingolimod; and a third group taking a higher dose of fingolimod. Eighty to 83% of those on either dose of fingolimod remained relapse-free over the year, compared to 69% of those on Avonex. Several longer phase III clinical trials are currently underway, including one involving people with primary progressive MS. And company press releases for both therapies suggested that they plan to apply for marketing approval at the end of 2009, to make the drugs available to the general public.

t hd Thompson

Habib

Denison

Job Title: MSC 0909 Progress Report Specs: 11 x 17” Newsletter (inside) Colors: Black & PMS 032

SUPPORTED BY BILLY TALENT & FRIENDS

Prenatal Exposure to Vitamin D May Lessen MS Risk Research funded in part by the MS Society of Canada has found evidence of a relationship between vitamin D and a common genetic variant which may alter the risk of developing multiple sclerosis. The research suggests that vitamin D deficiency during gestation and early childhood may increase the risk of a child developing the disease. University of Oxford researchers have shown that there is a direct relationship between DRB1*1501, a genetic variant associated with MS, and vitamin D. “This research represents an important development in our understanding of the cause of MS,” says Dr. Paul O’Connor, national scientific and medical advisor for the MS Society of Canada. “The evidence implicating vitamin D deficiency as a key factor in MS continues to mount,” says Dr. O’Connor. “Vitamin D insufficiency is emerging as a key factor of MS in children, and in adults. This finding links important work in two streams of research, namely genetics and epidemiology, and illustrates the important role the MS Society plays in solving what is a very complex disease.” Dr. O’Connor cautions that the study does not provide guidelines on vitamin D dosage and that any decisions on treatment or supplementation should be made in consultation with a trained physician.

Paper/Stock: 60# OFFSET Special Instructions: FOLDS IN HALF TO 8.5” x 11” AND AGAIN IN THIRDS

The MS Society of Canada Scholarship Program, supported by Billy Talent and Friends, is a post-secondary scholarship program for teens and young adults in Canada who have MS or who have a parent with MS. Last year, 80 young men and women received scholarships from the program. Below are excerpts from their own inspiring words on how MS has affected them.

Jessica Moskaluke, Saskatchewan Brandon University – Criminal Justice

Taylor McDonald, Ontario Durham College – Sports Administration

“When I was four years old, my father was diagnosed with MS. Eventually he became a paraplegic, and lost his ability to talk, feed himself, or even see… …When times get rough, I think of him and say, ‘Would he want me to feel sorry for myself?’ He never complained about his illness and he would want me to keep living my life the best I knew how.” When Jessica was 16 years old, she organized a rock concert and snowboard competition at the Asessippi Ski Lodge, with all proceeds going to the MS Society of Canada in memory of her father, Tim Moskaluke. “We raised about five thousand dollars, all of which went to the MS Society. I couldn’t have been happier, and although my dad wasn’t there with me, I know he guided me every step of the way.”

“Having your life affected by MS made me realize that it is the joy and love you bring to others that is the ultimate reward. My aunt has had MS since she was fifteen years old; my mom was diagnosed two years later at age nineteen… If you ever happen to meet me you will notice that I wear the red Hope – MS wristband in a reminder to be strong like my mother and aunt, to never give up and persevere through even the toughest of challenges.”

Kaitlin Curtiss, Ontario Brock University – Biology/Psychology “During my time with the doctors at the Hospital for Sick Children, I developed a keen interest in the field of pediatric neurology and a resolve to impact children’s lives as my doctors had impacted mine. While multiple sclerosis has had a profound effect on my physical state, it is not what defines me. I have still been able to live my life and will continue to do so regardless of the effects of MS.”

Tasli Shaw, British Columbia University of British Columbia – Psychology “The story of multiple sclerosis in my life lies within my mother, who has been under the grip of this chronic illness for nearly three decades… It is like having a troublesome relative over twenty-four hours a day, and try as we may, this is one relative that will not leave without a fight. MS has made my mother an immensely strong willed person, full of courage and determination. And despite the ongoing struggle my mother faces, through all the hardship day-to-day life throws at her, the single most outstanding gift she has given me is rock steady positivity. In scary and mysterious times, through the painful and traumatic events which come along with MS, my mother can smile.”

If you are interested in making a gift to the scholarship program, please contact: Nicole Mellin, Assistant Vice-President, National Client Services Research & Programs Phone: 1-866-922-6065, ext. 3004, [email protected]

Progress Report Vol 11

A Periodic Newsletter for Our Loyal Contributors

A Message from the President

D

R

I

V

FALL 2009

MS Society Announces New endMS Regional Research and Training Centres

E

Going Strong

The Multiple Sclerosis Society of Canada believes that collaboration is the quickest way to end MS! Yves Savoie

The MS Society of Canada’s Family & Friends Drive is in its 6th year! We’re so pleased with the success of this critical program, and grateful for every one of our volunteer participants. Just last year, the Family & Friends Drive went online, making it even easier to contact people you know who might be interested in supporting the MS Society. If you haven’t been called to participate, sign up online at www.mssociety.ca/en/give/family&friends.htm

A few tips for the upcoming Drive: • W  hen you’re asking your friends to support the MS Society, don’t forget that you might have some interested friends next door! Ask your neighbours to participate. • I f you belong to a book group or church group, let the other members know you’re raising money for MS. Every new supporter helps! • Look out for your volunteer kit in the mail.

A Monthly Donor on Giving to the MS Society Through our pre-authorized giving program, donors pledge their support on a monthly basis. It’s easy and convenient! As a monthly donor to the MS Society, you’ll ensure that we have a steady flow of funds for research. You’ll also receive a copy of our Annual Review, a complimentary pen set, invitations to participate in our teleconferences on MS research and bi-annual newsletter updates keeping you informed about the ongoing fight against MS. We spoke with Peter L. about why he chooses to make a monthly gift to the MS Society.

“I had actually forgotten that I was a monthly donor, since it’s so easy to just give and not think about it. It’s so much simpler than sending a cheque every few months. I don’t mind helping out; it is nice to be able to see some progress against a disease that is so much of a mystery.” Please help us make a cure for multiple sclerosis a reality with your pre-authorized gift – see the attached reply form, or visit us online at http://www.mssociety. ca/en/give/monthly-giving.htm

175 Bloor Street East, Suite 700 Toronto, Ontario M4W 3R8 Toll Free: (800) 361-2985

t hd Thompson

Habib

Denison

Job Title: MSC 0909 Progress Report Paper/Stock: 60# OFFSET Specs: 11 x 17” Newsletter (outside) Special Instructions: FOLDS IN HALF TO 8.5” x 11” AND AGAIN IN THIRDS Colors: Black & PMS 032

At the MS Society of Canada, we understand times are difficult for many Canadians. The global recession has taken a toll on all of us in some way. For our organization, the economy has had a direct impact on our ability to raise funds, threatening the research we fund and the services we provide. But multiple sclerosis does not relent in tough times, and neither will we. The MS Society remains committed to ending this disease! And we’re grateful and humbled that you are still with us. We know that what we are asking you to do now is more difficult than it was last year. Your support is more important than ever to the estimated 55,000-75,000 Canadians with MS. I hope you enjoy reading about our plans to keep fighting MS in this issue: from the studies we’ve helped fund, to the new network of endMS Regional Research and Training Centres we established earlier this year. And I also hope you will be touched by the personal stories from our scholarship recipients, whose lives your generosity has helped change. Thank you again for your support. It means so much.

Yves Savoie President and Chief Executive Officer Multiple Sclerosis Society of Canada MSC-NL4-F09

Canada is home to some of the best MS researchers in the world, spread across our vast country from Newfoundland to British Columbia. With the establishment of the endMS Research and Training Network and its five endMS Regional Research and Training Centres, our top researchers are now able to increase their collaboration and provide new education and training opportunities for research trainees. The five endMS RRTCs include over 100 affiliated researchers and 250 trainees. Researchers and trainees affiliated with each centre will collaborate, exchange information and increase their knowledge and skill in MS research through such activities as conferences, workshops, and inter-lab exchanges. Each centre comprises multiple academic institutions and teaching hospitals within a geographic region:

• Western-Pacific, covering British Columbia and Saskatchewan • Atlantic, covering the four Atlantic provinces • Manitoba-Ontario, excluding Ottawa • Quebec-Ottawa • Alberta

And for the next three years, each centre will receive $100,000 per year to fund research and training activities – funded entirely by the MS Society of Canada. The MS Society’s goal for the endMS Network is to accelerate discovery in the field of MS in Canada by increasing the capacity to conduct MS-focused research.